Matchday 2 of the 2021/22 Champions League group stages gets underway on Tuesday, with supporters across the continent hoping to see a continuation of the drama that unfolded in the first round of games.
Manchester United were shocked by Swiss champions Young Boys in the opening game of the competition, Milan almost mounted a famous comeback at Liverpool and Barcelona were humiliated by Bayern Munich - again.
There are plenty of intriguing storylines to keep track of this time around too, with Man City and PSG, Chelsea and Juventus and Man Utd and Villarreal all squaring off.
Here are your predictions and previews for all 16 ties.
Tuesday 28 September
Ajax vs Besiktas
When is it being played? Tuesday 28 September, 17:45 (BST)
Where is the match being played? Johan Cruyff Arena, Amsterdam
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Benoit Bastien (FRA)
VAR? Willy Delajod (FRA)
Ajax kicked off their Champions League campaign in incredible fashion during Matchday 1, with four goals from Sebastien Haller helping them to a 5-1 victory over Sporting.
Besiktas are dealing with a remarkable amount of injuries, so Erik ten Hag's side should make it two wins out of two on Tuesday.
Prediction: Ajax 3-1 Besiktas
Shakthtar Donetsk vs Inter
When is it being played? Tuesday 28 September, 17:45 (BST)
Where is the match being played? NSC Olimpiyskiy, Kyiv
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Istvan Kovacs (ROU)
VAR? Marco Fritz (GER)
Somehow, despite peppering the Real Madrid goal for 90 minutes, Inter came away empty handed last time out. Meanwhile, Shakhtar Donetsk were stunned by lowly Sheriff.
Expect the Nerazzurri to make up for disappointing last time out by getting off the mark in the Champions League here.
Read 90min's full match preview here.
Prediction: Shakhtar Donetsk 0-2 Inter
RB Leipzig vs Club Brugge
When is it being played? Tuesday 28 September, 20:00 (BST)
Where is the match being played? Red Bull Arena, Leipzig
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Slavko Vincic (SVK)
VAR? Paolo Valeri (ITA)
Club Brugge picked up a very credible draw against Paris Saint-Germain last time out, suggesting that they will not be whipping boys this season.
RB Leipzig know victory is a must here if they are to have any chance of securing a top two spot spot over City and PSG. They have not been brilliant this season but home advantage should see them get the three points.
Prediction: RB Leipzig 2-1 Club Brugge
Paris Saint-Germain vs Manchester City
When is it being played? Tuesday 28 September, 20:00 (BST)
Where is the match being played? Parc des Princes, Paris
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Carlos del Cerro Grande (ESP)
VAR? Juan Martinez Munuera (ESP)
In what is the undoubted standout fixture of the week, PSG host City on Tuesday evening in a game that combines on-field and geopolitical rivalries.
City got the better of their opponents in last year's semi-finals and despite the Parisians' strong start to the domestic campaign, we are not expecting anything different this time out.
Read 90min's full match preview here.
Prediction: Paris Saint-Germain 1-3 Manchester City
AC Milan vs Atletico Madrid
When is it being played? Tuesday 28 September, 20:00 (BST)
Where is the match being played? San Siro, Milan
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Cuneyt Cakir (TUR)
VAR? Abdulkadir Bitigen (TUR)
This is set to be an intriguing tie as both Milan and Atletico Madrid know this is a must-win game with Liverpool likely to take top spot in Group B.
Both sides love to counter, so they could end up cancelling each other out in the end.
Read 90min's full match preview here.
Prediction: AC Milan 1-1 Atletico Madrid
Porto vs Liverpool
When is it being played? Tuesday 28 September, 20:00 (BST)
Where is the match being played? Estadio do Dragao, Porto
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Sergei Karasev (RUS)
VAR? Bastian Dankert (GER)
After edging to a 3-2 win over Milan at Anfield last time out, Liverpool will want a more controlled display when they travel to Porto on Tuesday.
The Portuguese side are unbeaten this season and have defended especially well. Do they have enough to keep the Reds out, though? Maybe not.
Read 90min's full match preview here.
Prediction: Porto 0-3 Liverpool
Borussia Dortmund vs Sporting CP
When is it being played? Tuesday 28 September, 20:00 (BST)
Where is the match being played? Signal Iduna Park, Dortmund
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Srdjan Jovanovic (SRB)
VAR? Pol van Boekel (NED)
Jude Bellingham put in one of the best displays of his young career against Besiktas on Matchday 1 and Erling Haaland was also impressive.
If Dortmund are to secure a second successive Champions League win, expect the young pair to be at the centre of things.
Prediction: Borussia Dortmund 3-2 Sporting
Real Madrid vs Sheriff Tiraspol
When is it being played? Tuesday 28 September, 20:00 (BST)
Where is the match being played? Santiago Bernabeu, Madrid
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Lawrence Visser (BEL)
VAR? Clement Turpin (FRA)
Sheriff's opening day victory was one of the feelgood moments of the season so far but they are in for a far stiffer test this time out.
Real Madrid away is what dreams are made of, but it could easily turn into a nightmare if they are not careful.
Read 90min's full match preview here.
Prediction: Real Madrid 4-0 Sheriff Tiraspol
Wednesday 29 September
Atalanta vs Young Boys
When is it being played? Wednesday 29 September, 17:45 (BST)
Where is the match being played? Gewiss Stadium, Bergamo
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Felix Brych
VAR? Sascha Stegemann
Young Boys got their European journey off to a dream start against Manchester United, stunning the 10-man Red Devils with a 2-1 victory.
Completing the trick against an Atalanta side held to a 2-2 draw with 10-man Villarreal last time out could prove challenging, even if La Dea are not quite firing on all cylinders just yet.
Prediction: Atalanta 1-0 Young Boys
Zenit St Petersburg vs Malmo
When is it being played? Wednesday 29 September, 17:45 (BST)
Where is the match being played? Gazprom Arena, St Petersburg
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Anastasios Sidiropoulos
VAR? Jose Maria Sanchez Martinez
This looks like a game that will go a long way to deciding who finishes third - behind Chelsea and Juventus - in the group.
On paper Zenit are a much stronger side and one would expect them to flourish at home.
Prediction: Zenit St Petersburg 2-0 Malmo
Benfica vs Barcelona
When is it being played? Wednesday 29 September, 20:00 (BST)
Where is the match being played? Estadio da Luz, Lisbon
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Daniele Orsato
VAR? Massimiliano Irrati
We could have an upset on our hands here...
Benfica have been flawless in the league this season and should have won against Dynamo Kyiv last time out. Meanwhile, Barcelona are in the midst of an injury crisis and were humbled by Bayern Munich on Matchday 1. At least Ansu Fati is back for the visitors.
Prediction: Benfica 2-1 Barcelona
Bayern Munich vs Dynamo Kyiv
When is it being played? Wednesday 29 September, 20:00 (BST)
Where is the match being played? Allianz Arena, Munich
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Marco Guida
VAR? Maurizio Mariani
Dynamo Kyiv need a minor miracle to prevent Champions League favourites Bayern Munich doing the business on home ground.
Robert Lewandowski will be eager to close the gap on Haller in the Golden Boot race too.
Read 90min's full match preview here.
Prediction: Bayern Munich 4-0 Dynamo Kyiv
Manchester United vs Villarreal
When is it being played? Wednesday 29 September, 20:00 (BST)
Where is the match being played? Old Trafford, Manchester
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Felix Zwayer
VAR? Christian Dingert
Just a few months on from their meeting in the Europa League final, United host Villarreal in the continent's premier club competition.
The Yellow Submarine secured bragging rights last time out, but they are faltering this season, picking up five draws from their opening six La Liga matches. Another tie is likely the best they can hope for from this one.
Read 90min's full match preview here.
Prediction: Manchester United 1-1 Villarreal
Red Bull Salzburg vs Lille
When is it being played? Wednesday 29 September, 20:00 (BST)
Where is the match being played? Red Bull Arena, Salzburg
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Halil Umut Meler
VAR? Mete Kalkavan
Red Bull Salzburg have their best ever chance to qualify for the Champions League knockout stages this season and got off to a good start in Matchday 1, securing a 1-1 draw with Sevilla.
Lille, who also drew last time out, are their next opponents in what looks like it will be an even but entertaining contest.
Prediction: Red Bull Salzburg 2-2 Lille
Wolfsburg vs Sevilla
When is it being played? Wednesday 29 September, 20:00 (BST)
Where is the match being played? Volkswagen Arena, Wolfsburg
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Georgi Kabakov
VAR? Kevin Blom
The other game in the most open Champions League group of the season sees Wolfsburg take on Sevilla.
This is another open tie that is extremely tough to call, with both sides looking strong on paper. A draw seems most likely.
Prediction: Wolfsburg 0-0 Sevilla
Juventus vs Chelsea
When is it being played? Wednesday 29 September, 20:00 (BST)
Where is the match being played? Allianz Stadium, Turin
What TV channel is it on? BT Sport (UK), Paramount+ (US), DAZN (Canada)
Referee? Jesus Gil Manzano
VAR? Juan Martinez Munuera
Juventus' start to the season has been putrid with the Old Lady already losing twice and only narrowly beating Spezia and Sampdoria in their last two games.
Meanwhile, Chelsea are flying and should be able to dispatch of Juve - even though they are the away side.
Prediction: Juventus 1-3 Chelsea
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Source : 90min