Juliano Belletti's sensational first-half strike illuminated a fine game which means the north London side have failed to beat Chelsea in 21 encounters at Stamford Bridge going back to 1990.
Aaron Lennon produced a mazy run on ten minutes, slicing through the Chelsea rearguard before arrowing in a fine right-footed byline cross.
Thankfully for Chelsea, Ricardo Carvalho was alert enough to intercept the ball and clear for a corner.
The home side, for their part, quickly settled into their familiar passing mode and, on 19 minutes, took the lead.
Belletti picked the ball up on the halfway line and raced forward. The Brazilian full-back unleashed an unstoppable right-footed 30-yard shot which curled in mid-flight away from the despairing dive of Radek Cerny and into the top left-hand corner of the net.
Cech, returning from injury, produced a fine save from Steed Malbranque's 28th-minute volley after excellent set-up play by Lennon.
Michael Ballack had the ball in the net on 43 minutes but was offside after Florent Malouda had slid the ball on to the Chelsea captain.
Joe Cole had the first effort on target in the second half, but Cerny comfortably handled his weak, left-footer from the edge of the Spurs penalty area.
Chelsea new boy Nicolas Anelka entered the fray on 57 minutes, replacing Claudio Pizarro.
The £15million hit-man was quickly into the action and forced a brilliant save from Cerny after the ex-Bolton man's turn and left-foot drive from just inside the penalty area had looked good for a goal.
Spurs countered with a period of good possession that resulted in them winning a succession of corners.
Chelsea however dealt with the threats, which were never clear chances.
Spurs had a wonderful chance to equalise on 70 minutes but Dimitar Berbatov, quiet up until that point, sent a curling free-kick just inches over the Chelsea crossbar.
Robbie Keane was unlucky not to get to Lennon's excellent cross on 79 minutes after Alex mistook the flight of the ball and let it get past him.
But seconds later Chelsea sealed the game. A quick throw-in by Belletti found Joe Cole.
The midfielder found Wright-Philips who rammed the ball home with a fine daisy-cutter from the edge of the area past Cerny's dive.
Anelka hit the woodwork in the last minute but Chelsea were worthy winners.