Jose Mourinho will rest his two star men and goalkeeper Petr Cech.
Carlo Cudicini will take his place between the sticks with Glen Johnson and Paulo Ferreira returning to the fold to fight for the right-back berth
Wayne Bridge is expected to return to left-back while fourth-choice striker Carlton Cole will star up front.
With so many changes, so so-called experts will be expecting a possible upset, but Mourinho has stated that he expects each player to play to their maximum.
"If they want to be part of Chelsea's future and to play in the Premiership, then they will have to perform in the cup.
"I expect them to perform well."