The Colombian winger has been strongly linked with a move to the Barclays Premier League leaders in the winter transfer market and has a buy-out clause set at Â£26.8million.
Chelsea have reportedly offered Â£20million to acquire Cuadrado, who is tied to the Viola until June 2019.
When asked about the English club's interest in Cuadrado, Della Valle told the club's official website: "The buy-out clause is there.
"We put it (buy-out clause) high in order to keep him (Cuadrado).
"I hope he will stay with us for a long time."
Cuadrado was one of the stand-out players alongside James Rodriguez for Colombia in last year's World Cup in Brazil.
The 26-year-old joined Fiorentina in 2012 from Udinese and has been a regular in Vincenzo Montella's side since.
The Colombian has scored four goals and set up four more in 16 league appearances for Fiorentina this season.
Cuadrado started in Sunday's 1-1 draw against Roma that lifted the Florence outfit to sixth in the Serie A table.
Fiorentina have qualified for the quarter-finals of the Coppa Italia and will take on Tottenham in the last 32 of the Europa League next month.
Source : PA