The Ukrainians sit second in Group G, one place ahead of Chelsea, at the halfway stage and a victory for the visitors would make a significant dent in their hosts' bid for the knockout stages.
It could also further endanger Mourinho's perilous position as Blues boss.
Rebrov said: "It's a little bit funny, ridiculous that I have to constantly answer the questions about Mourinho.
"Fifty percent of questions are about Mourinho."
The former Tottenham and West Ham striker, who enjoyed a fine strike partnership with ex-Chelsea striker Andriy Shevchenko during the pair's playing days, is looking to add to Mourinho's woes.
The Blues have lost nine times in 17 games in all competitions this term and sit 15th in defence of their Premier League title.
"We really shouldn't be thinking about what's happening with Chelsea at the moment
What is happening with them now can happen to anyone," Rebrov added.
"We need to focus on our game and not to think whether it's a wounded animal or not.
"We didn't think about that in Kiev and we won't tomorrow.
"We wish Chelsea to do very well in the Premier League but not tomorrow."
Mourinho earlier on Tuesday said he would be satisfied with a draw, believing the Blues would still qualify by beating Maccabi Tel-Aviv and Porto in their remaining games.
Chelsea began with a 4-0 win over Maccabi Tel-Aviv before losing in Porto and drawing in Kiev.
Rebrov would not be happy with a point, though.
He said: "Of course we will not be happy with a draw
We weren't happy with the draw in Kiev.
"We'll play to win this game tomorrow and you'll see Dynamo attacking.
"The main thing is not only to attack and to win, but to play as a team."
Key to Kiev's performance is Andriy Yarmolenko, who performed well in Ukraine and has been the subject of transfer interest from numerous Premier League clubs.
The forward recently signed a new five-year contract and Rebrov wishes to keep him.
"If you ask me I want to keep him, but it all depends on his relationship with the president," the head coach added.
Brazilian full-back Danilo Silva is the only absentee for Dynamo.
He stayed behind as his pregnant wife went into labour, meaning Antunes is likely to start at left-back, with Croatian Domagoj Vida on the right.
Source : PA