Fans were infuriated by the 2-0 home defeat by Swansea in the Capital One Cup last Wednesday. Fernando Torres' poor performance in the semi-final first leg was explained by a stomach bug, with Demba Ba's minor hamstring injury preventing the introduction of the £7million signing from Newcastle until the final 10 minutes.
Both strikers are available against the Saints and Benitez is likely to opt for Ba. Benitez was criticised for using Torres and Ba's injuries as excuses for last week's cup setback, but the Spaniard said: "I was surprised the other day when I spoke about Fernando's problems with his stomach (and that) we couldn't play Demba Ba because he had a niggle."
He continued: "Afterwards it was said I was making excuses, but I wasn't making excuses. I am still being criticised for making the decision to play Fernando Torres instead of Demba Ba, who was a big risk if he got injured.
"If you know Demba Ba could be injured, it is my job as manager to make this decision. He scored two against Southampton (in the FA Cup) but couldn't play the next game against Swansea because of a niggle. If we can continue winning games, it's not a case of I can't win."
Benitez and chairman Bruce Buck were jeered by disgruntled supporters after losing to Swansea and their anger has been only temporarily appeased by Saturday's 4-0 romp at Stoke.
Successive home defeats to QPR and Swansea, while failing to score, ensures Chelsea must find a way through what Benitez expects to be a congested Southampton defence.
"We are doing well away but at home other teams play deep and wait and there's less space," he said. "We are still creating chances but the main thing is to be more clinical.
"If we take our chances it will be totally different because the teams we play will be more open and we will have the space we're looking for. But if that's not the case, as in the last two games, it is more difficult.
"If a team puts 11 players behind the ball you have to find the space and be more precise."